姓名：徐立紅
性別：女
籍貫：河南
所屬學(xué)科：生物化學(xué)與分子生物學(xué);勞動衛(wèi)生與環(huán)境衛(wèi)生學(xué)
職稱：教授、博導(dǎo)
現(xiàn)任職務(wù)：生物化學(xué)與分子生物學(xué)教研室主任，勞動衛(wèi)生與環(huán)境衛(wèi)生研究所副所長
聯(lián)系方式：
電話：
手機：13067709966
E－mail:xulihong@zju.edu.cn
學(xué)術(shù)團體和社會兼職：中國環(huán)境科學(xué)學(xué)會理事;中國環(huán)境誘變劑學(xué)會理事
學(xué)科專長：環(huán)境毒理學(xué)、生化毒理學(xué)
在研課題：
1.國家自然科學(xué)基金重點項目“典型化合物的環(huán)境危險性評價方法學(xué)基礎(chǔ)研究”
2.863項目“用蛋白磷酸酶抑制法對毒素進行定性定量測定”
3.教育部博士點基金項目：微囊藻毒素對細(xì)胞凋亡的干擾及其致毒機理探討
研究方向：
1.外源性物質(zhì)對細(xì)胞信號轉(zhuǎn)導(dǎo)和細(xì)胞凋亡的影響，毒理－蛋白質(zhì)組學(xué)。
2.細(xì)胞信號轉(zhuǎn)導(dǎo)與疾病、細(xì)胞凋亡與疾病、疾病蛋白質(zhì)組學(xué)、疾病的分子診斷。
最后學(xué)歷：博士
簡歷：
1985-1999.8 中科院水生生物研究所
1999.9-2003.6 浙江大學(xué)醫(yī)學(xué)院公共衛(wèi)生系
2003.6-至今 浙江大學(xué)醫(yī)學(xué)院基礎(chǔ)醫(yī)學(xué)系
1986-1987 美國環(huán)保局德魯斯實驗室參加合作研究一年
1994年 日本名城大學(xué)藥學(xué)系進行合作研究三個月
1995年 香港城市大學(xué)生物及化學(xué)系進行合作研究一個月
1997-1998年 香港城市大學(xué)生物及化學(xué)系做博士后一年
業(yè)績一覽：
一、發(fā)表文章
1．Xu Lihong, Zhang Yongyuan,, Paul K S Lam, Rudoff Wu, Ken-ichi Harada。Study of using fish protein phosphatase assay as biomarker to monitor okadaic class tumor rpomoters in water.“Asia Pacific Conference on Science and Management of Coastal Environment. Hong Kong, 1996”和“International Symposium on Environmental Chemistry and Toxicology, Sydney, Austrlia,1996”(墻報).
2．Xu Lihong，Zhou Bingsheng，Paul K S Lam, Chen Jiaping, Zhang Yongyuan, Ken-ichi Harada。 Study about intoxication mechanism of microcystins on fish. 3rd International Symposium on Aquatic Animal Health, 1998,Baltiomore, Maryland, USA (分會口頭報告)
3．Xu Lihong, Zhang Yongyuan and Wang Deming。Fish enzymatic indicators in aquatic toxicology. The First Internationnl Symposium on fish Physiology. Fish Toxicology, and Fisheries Management, Guangzhou, PRC. (特邀報告), 1988.
4．Xu Lihong, Zhang Yongyuan, Xu Ying and Chen Zhuan. Effects of new insecticide CCU on Carps: acute toxicity and metabolism in vitro. Proceedingsof2nd international Symposium on fish Physiology, Fish Toxicology, and water quality Management, Sacromento, USA.(特邀報告)1990
5．張瑞祥，陶小南，張勁農(nóng), 向敏，張甬元，徐盈，徐立紅, 液相色譜測定白三烯及其在臨床和實驗中的應(yīng)用, 第一屆國際華人胸肺疾病研討會,1990.
6．張甬元，徐立紅，徐盈，陳專。滅幼脲Ⅲ號在魚體中的殘留及代謝的研究. 全國環(huán)境生態(tài)毒理學(xué)會議, 1992
7．Ying Yiwei，Wang Zhaohui，Zhang Yongyuan，Xu Ying，Xu Lihong，Wu Wenzhong，Chen Guosheng。Ecotoxicoogical study of fenpropathrin on some common chinese aquatic organisms and evaluation of its effect on aquatic ecosystem. 3rd international sympoium fih phyiology toxicology and water quality management. Nanjin,PRC (特邀報告),1992
8．Xu Lihong，G J Zheng, P.K.S Lam, B.J Richardson, 1999. Relationship between tissue concentrations of polycyclic aromatic hydrocarbons and DNA adducts in green- lipped mussels (Perna viridis), Ecotoxicology, 8,73-82.
9．Xu Lihong, P K S Lam, Chen J P, Zhang Y Y, K-I Harada, 2000. Comparative Study on in vitro Inhibition of Fish and Mouse Protein Phosphatases by Microcystins, Environmental Toxicology, 5, 71-75.
10．Xu Lihong P K S Lam, Chen J P, Xu J M, Wong B S F, Zhang Y Y, R S S Wu and K-I Harada, 2000. Use of protein phosphatase inhibition assay to detect microcystins in Donghu Lake and a fish pond in china, Chemosphere,41,53-58. 11．Xu Lihong Zheng J S，Zhang Y Y, C C C Cheng and P K S Lam, 2001 Biomarker studies on gold-lined sea bream (Rhabdosargus sarba) exposed to benzo[a]pyrene. Water Science and Technology, 43:155-160.
12．Xu Lihong, Zhang, Y.Y., Lam, P.K.S. and Wong, B.S.F. 2001. Investigations on microcystins in Chinese water bodies - a review. Pp. 289-298. (Ed. B.M. Gawlik, B. Platzer & H. Muntau). In Freshwater Contamination in China: Current topics of research. Environment and Quality of Life Series. European Commission. (invited paper)
13．Xu Lihong, Zhou, B., Lam, P.K.S., Chen, J., Zhang, Y. and Harada, K.-I. 2002. In vivo protein phosphatase 2A inhibition and glutathione reduction by microcystin-LR in grass carp (Ctenopharyngodon idellus). In Proceedings of the Ninth International Conference on Harmful Algal Blooms, Hobart, Australia, 7-11 February 2000. (Ed. Hallegraeff, G.M., Blackburn, S., Bolch, C.J. and Lewis, R.) Pp. 399-402. Published by Intergovernmental Oceanographic Commission of UNESCO.
14．Bryan Wong, Paul K S Lam, Xu Lihong et al 1999. A colorimetric assay for screening microcystin class compounds in aquatic systems, Chemosphere,38,1113-1122.,
15．Chen G S, Xu Y, Xu Lihong et al Influence of dioxin and metal-contaminated sediment on phase I and II biotransformation enzymes in silver crucian carp, Ecotoxicology and Environmental Safety, 1998.,
16．Eric W.K. Ching, William H.L. Siu, Paul K.S. Lam, Xu Lihong et al, 2001. DNA Adduct Formation and DNA Strand Breaks in Green-lipped Mussels (Perna viridis) Exposed to Benzo[a]pyrene: Dose and Time Dependent Relationships, Marine Pollution Bulletin 42,603-610
17．W.H.L. Siu, J. Cao, R.W. Jack , R.S.S. Wu, B.J. Richardson, 徐立紅, P.K.S. Lam. Application of the comet and micronucleus assays to the detection of B[a]P genotoxicity in haemocytes of the green-lipped mussel (Perna viridis) ,Aquatic Toxicology 66 ，2004，66：381–392.（SCI收錄)
18．Xiaowei Zhang, Rudolf S.S. Wu, Wenyu Fu, 徐立紅 , Paul K.S. Lam Production of reactive oxygen species and 8-hydroxy-20deoxyguanosine in KB cells co-exposed to benzo[a]pyrene and UV-A radiation Chemosphere (2004) 55: 1303–1308
