孫曉溪,男,博士,主任醫(yī)師,中心主任,F(xiàn)就職于中福會國際和平婦幼保健院生殖醫(yī)學(xué)中心。
招生專業(yè):婦產(chǎn)科 生殖醫(yī)學(xué)
研究方向:人類輔助生殖技術(shù)及相關(guān)領(lǐng)域的臨床和基礎(chǔ)研究。
特色和手段:
通過應(yīng)用體內(nèi)外實驗、細(xì)胞培養(yǎng)和分子生物學(xué)技術(shù),對不孕癥、反復(fù)自然流產(chǎn)以及與人類輔助生殖技術(shù)相關(guān)的領(lǐng)域進(jìn)行臨床和基礎(chǔ)研究。
意義:探索不孕癥、反復(fù)自然流產(chǎn)的發(fā)病機(jī)理;改善輔助生殖技術(shù)妊娠成功率。
近年國內(nèi)外發(fā)表的重要論文和專著:
1.Xiaoxi Sun, Kristina Gemzell-Danielsson, Hong Zhen Li, Berit Stabi and Anneli Stavreus-Evers. Expression of heparin-binding epidermal growth factor-like growth factor and its receptors in the human fallopian tube and endometrium after treatment with mifepristone. FERTILITY AND STERILITY, 2006,85(1): 171-178.
2.Xiaoxi Sun, Xiaoyan Qiu, and Kristina Gemzell-Danielsso. Effects of mifepristone on expression of endothelial nitric oxide synthase in human endometrium during the implantation phase. FERTILITY AND STERILITY, 2003,80(6): 145-160
3.Xiaoxi Sun, Alexander Christow, Lena Marions, Kristina Gemzell-Danielsson. Progesterone receptor isoform B in the human Fallopian tube and endometrium following mifepristone. Contraception, 67 : 319-326,2003.
4.Xiaoyan Qiu, Xiaoxi Sun, Alexander Christow, Berit St?bi, and Kristina Gemzell-Danielsson. Action of mifepristone on the expression of insulin-like growth factor binding protein-1 mRNA and protein during the early luteal phase in the human oviduct. FERTILITY AND STERILITY, 2003,80(suppl 2): 776-782.
5.H.Z.Li, X.Sun, A.Stavreus-Evers and K.Gemzell-Danielsson. Effect of mifepristone on the expression of cytokines in the human Fallopian tube. Mol Hum Reprod. 2004 Jul;10(7):489-93.
6.Dajin LI, Xiaoxi SUN, Chaojing Li, Lirong Cai, Yi Meng. Effects on Fertility of Immunizing Mice with Anti-idiotypic Antibodies to Porcine Zona Pellucida Antigen. J Reprod Immunol 2002; 54:81-92.
7.Christow A, Sun X, Gemzell-Danielsson K. Effect of mifepristone and levonorgestrel on expression of steroid receptors in the human Fallopian tube. Mol Hum Reprod. 2002 Apr;8(4):333-40.
8.Xiaoyan Qiu, Xiaoxi Sun, Alexander Christow, Berit St?bi and Kristina Gemzell-Danielsson. The effect of mifepristone on the expression of insulin-like growth factor binding protein-1, prolactin and progesterone receptor mRNA and protein during the implantation phase in human endometrium. Mol Hum Reprod.2002 Nov;8(11):998-1004.
9.Marions L, Hultenby K, Lindell I, Sun X(孫曉溪), Stabi B, Gemzell Danielsson K. Emergency contraception with mifepristone and levonorgestrel: mechanism of action. Obstet Gynecol 2002 Jul;100(1):65-71.
10.Lu LI, Xiao-xi Sun, Jun-ling CHEN, Xiao-hong GAO,Yong-wei WANG,Jie-wei TAO, Li-nan CHENG. Analysis of factors influencing pregnancy rate in frozen-thawed embryo tansfer. Journal of 《Reproductin and Contraception》 2004;15(4):239-244
11.陳秋菊,孫曉溪,程利南. 卵巢過度刺激綜合征的研究進(jìn)展. 《生殖醫(yī)學(xué)雜志》 2006;15(5):373-377
12.陳秋菊,孫曉溪,程利南. 卵巢刺激周期的子宮內(nèi)膜接受性及其標(biāo)志物. 《國外醫(yī)學(xué)計劃生育分冊》2006;25(5):253-260
13.徐步芳,孫曉溪,程利南. 反復(fù)自然流產(chǎn)與子宮內(nèi)膜接受性. 國外醫(yī)學(xué)計劃生育分冊,2005,24(3):138-141
14.李路,孫曉溪,陳軍玲,石林特,高曉紅,王永衛(wèi),陶皆惟,程利南.影響冷凍胚胎移植妊娠率相關(guān)因素的分析 《生殖與避孕》 2004;12(8):218-221
15.李路,孫曉溪,陳軍玲,高曉紅,王永衛(wèi),陶皆惟,程利南.低劑量緩釋型去普瑞林在體外受精胚胎移植中的評價 《生殖醫(yī)學(xué)雜志》 2005;14(8)
16.高曉紅、孫曉溪、石林特、李路、陳軍玲、王永衛(wèi)、程利南.體外受精-胚胎移植術(shù)后妊娠結(jié)局回顧分析 《生殖與避孕》 2004;24(1):39-42
17.吳煜,高曉紅,孫曉溪. 胚胎移植技術(shù)對體外受精-胚胎移植結(jié)果的影響-653例臨床分析. 《生殖與避孕》 2005, 25(8)
18.李路、陳軍玲、石林特、高曉紅、王永衛(wèi)、陶皆惟、孫曉溪、程利南 贈卵體外受精臨床療效的評估!稄(fù)旦學(xué)報》(醫(yī)學(xué)版) 2004; 31( 1):74-76
19.陳軍玲、石林特、李路、高曉紅、顧一春、孫曉溪、程利南 300對不孕癥夫婦對試管嬰兒中心選擇的因素分析!吨袊】惦s志》2004;15(3):154-158
獲獎情況:
"卵透明帶抗獨(dú)特型抗體免疫抗生育作用的研究"獲上海醫(yī)學(xué)科技獎 三等獎 2003年
招生要求:
熱愛本職工作,具有2年以上婦產(chǎn)科臨床工作經(jīng)驗或有生殖生物學(xué)、分子生物學(xué)和細(xì)胞生物學(xué)專業(yè)背景
聯(lián)系方式:電子郵箱:sun_xx@hotmail.com
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